Conditions We Treat

Atypical Wounds

At Physicians Wound Treatment of Tampa (PWTT), we specialize in diagnosing and treating atypical wounds—wounds that do not follow the usual healing process and may be caused by underlying medical conditions. Our team, led by one of Tampa’s only board-certified wound specialists, provides expert care to ensure proper diagnosis and advanced treatment for these complex wounds.

Atypical Wound -Pyoderma Gangrenosum Ulcer

What Are Atypical Wounds?

Atypical wounds are chronic, non-healing ulcers that arise from conditions unrelated to pressure, arterial, venous, or diabetic causes. These wounds may result from autoimmune diseases, infections, malignancies, or inflammatory disorders and often require specialized treatment.

Causes of Atypical Wounds

Atypical wounds can develop due to:

  • Autoimmune & Inflammatory Diseases: Conditions like lupus, vasculitis, and pyoderma gangrenosum that cause excessive immune system reactions.
  • Infections: Bacterial, fungal, or viral infections that impair skin integrity.
  • Malignancies: Certain cancers, such as squamous cell carcinoma, can manifest as chronic non-healing wounds.
  • Drug Reactions: Some medications can cause skin ulcers as a side effect.
  • Genetic or Metabolic Disorders: Conditions such as sickle cell disease that affect skin healing and regeneration.

Symptoms of Atypical Wounds

Signs that a wound may be atypical include:

  • Persistent, non-healing ulcers despite standard treatment
  • Unusual wound appearance (e.g., raised, undermined edges or excessive tissue destruction)
  • Extreme pain or minimal pain that seems disproportionate to the wound size
  • Rapid deterioration without an obvious cause
  • Associated systemic symptoms, such as fever, fatigue, or joint pain

Treatment Options for Atypical Wounds

At PWTT, we use a multidisciplinary approach to diagnose and treat atypical wounds effectively, including:

  • Comprehensive Diagnostic Testing: Biopsies, blood work, and imaging to identify underlying conditions.
  • Targeted Medical Therapy: Immunosuppressive treatments, antibiotics, or anti-inflammatory medications tailored to the wound’s etiology.
  • Advanced Wound Care: Debridement, specialized dressings, and cellular-based therapies to support healing.
  • Advanced treatments such as UVC (Ultraviolet C) light therapy to kill bacterial and viral pathogens including MRSA and VRE and low frequency ultrasound to promote deposition of granulation tissue and increase angiogenesis.
  • Pain Management & Long-Term Care Planning: Customized strategies to address discomfort and

    prevent recurrence.

FAQs About Atypical Wounds

If a wound is not healing despite appropriate care, or if it has an unusual appearance, a specialist evaluation is recommended.
Yes, with proper diagnosis and targeted treatment, many atypical wounds can heal successfully.
Identifying the underlying cause early prevents complications and ensures the most effective treatment plan.

At PWTT, we are committed to delivering expert wound care and innovative treatments to help you heal faster and regain your quality of life.

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Common Conditions We Treat

Arterial Wounds

Atypical Wounds

Diabetic Wounds

Lymphatic Wounds

Pressure Wounds

Trauma Wounds